Parameter Balancing


Parameter balancing is a computational method for obtaining consistent parameter sets for kinetic metabolic models. Experimentally measured values, when inserted into models directly, would be likely to yield incomplete and inconsistent parameter sets. Balanced parameter sets, computed from measured kinetic constants and other experimental data, respect constraints between biochemical quantities and assumptions about typical ranges, represented by prior values and bounds.  An online tool as well as Python and Matlab code are provided.

Phare Software